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1A. Estrogen

Type of Estrogen

Starting dose*

Oral

Conjugated estrogen (PremarinⓇ)

0.3 – 0.625 mg daily

17β-estradiol (EstraceⓇ)

0.5 – 1 mg daily

Transdermal Patch

17β-estradiol (EstradotⓇ, OesclimⓇ, generic)

25 – 50 mcg twice weekly

17β-estradiol (ClimaraⓇ)

25 – 50 mcg once weekly

Transdermal Gel

17β-estradiol (EstrogelⓇ)

1 pump = 0.75 mg 17β-estradiol 

1 – 2 pumps daily

17β-estradiol (DivigelⓇ)

0.5 – 1 mg sachet daily

*Starting doses may be higher when treating premature ovarian insufficiency (POI).

For a full listing of hormonal products and non-hormonal medication options click here.

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